PT-141 10 mg
Research PeptidePT-141 (Bremelanotide) 10 mg x 10 vials — Research-Grade Melanocortin Receptor Agonist (MC3R/MC4R)
Document ID: HKPW-pt-141-10-mg-research-peptide-usa-v1.0 | Reviewed: HKPEPTIDE WORLDWIDE Research Team | Updated: 2026-08-08
Product Identity & Specifications
| Parameter | Specification |
|---|---|
| Product | PT-141 (Bremelanotide) |
| Dosage | 10 mg x 10 vials |
| CAS | 189691-06-3 |
| Formula | C50H68N14O10 |
| MW | ~1,025.2 Da |
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| Purity | ≥99% HPLC |
| Appearance | White to off-white lyophilized powder |
| Solubility | Sterile water or bacteriostatic water |
| Storage | 2–8°C, desiccated, protected from light |
| Class | Melanocortin Receptor Agonist (MC3R/MC4R) |
Research Background
PT-141 is a cyclic heptapeptide melanocortin receptor agonist selective for MC3R and MC4R. Unlike Melanotan-II (which activates MC1R causing pigmentation), PT-141 was engineered for CNS melanocortin receptor selectivity. Research applications focus on central melanocortin pathways regulating sexual arousal independent of dopaminergic and serotonergic systems.
The 10 mg x 10 vials configuration is manufactured under strict quality control with HPLC, MS, and AAA verification. Batch-specific COA included. Bulk and OEM configurations available.
Molecular Mechanisms
MC3R/MC4R Activation
Selective agonism at central melanocortin receptors in hypothalamic and limbic regions modulating sexual arousal pathways.
Non-Dopaminergic Mechanism
PT-141 activates melanocortin pathways distinct from dopaminergic agents providing a tool for studying melanocortin-mediated sexual behavior.
Cyclic Peptide Stability
The Asp2-Lys7 lactam bridge creates a constrained cyclic conformation enhancing metabolic stability and receptor selectivity.
Research Applications
- Central Melanocortin Signaling
- MC3R/MC4R Pharmacology
- Sexual Function Neurobiology
Comparative Analysis
Compared to Melanotan-II: PT-141 has greater MC4R selectivity and reduced MC1R activation reducing pigmentation effects. Both are cyclic melanocortin analogues.
Quality Specifications
| Parameter | Method | Specification |
|---|---|---|
| Purity | HPLC 214nm C18 | ≥99.0% |
| Identity | ESI-MS | ~1,025.2 Da |
| Appearance | Visual | White to off-white powder |
| Peptide Content | AAA | ≥80% net peptide |
| Moisture | Karl Fischer | ≤3% |
| Endotoxin | LAL | ≤0.5 EU/mg |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 10 mg x 10 vials × 10 vials | Evaluation |
| Bulk Kit | Custom × 10 vials | Chronic studies |
| OEM | Custom | Branded products |
FAQ
Q: PT-141 vs Melanotan-II?
PT-141 has enhanced MC3R/MC4R selectivity with reduced MC1R activation. Melanotan-II is less selective and activates MC1R more strongly causing pigmentation.
Wholesale Pricing
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
Related Research & Resources
| Resource | Description |
|---|---|
| Healing Regenerative Peptides Hub | Complete research overview & methodology hub |
| Pt 141 10 Mg Research Peptide Usa | Related research peptide product |
| Aicar 5 Mg Research Compound Usa | Related research peptide product |
| Peptides In Skincare And Weight Loss Research | Latest research insights & methodology |
View Complete Research Guide »
Compliance
FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use. Not a dietary supplement or pharmaceutical.
© 2026 HKPEPTIDE WORLDWIDE. Document ID: HKPW-pt-141-10-mg-research-peptide-usa-v1.0