Glutathione (GSH) 1500 mg — Research-Grade Endogenous Antioxidant Tripeptide

Document ID: HKPW-glutathione-1500-mg-research-compound-us-v1.0 | Reviewed: HKPEPTIDE WORLDWIDE Research Team | Updated: 2026-08-08

Product Identity & Specifications

Parameter	Specification
Product	Glutathione (GSH)
Dosage	1500 mg
CAS	70-18-8
Formula	C10H17N3O6S
MW	~307.3 Da
Sequence	gamma-L-Glutamyl-L-cysteinylglycine
Purity	≥99% HPLC
Appearance	White to off-white lyophilized powder
Solubility	Sterile water or bacteriostatic water
Storage	2–8°C, desiccated, protected from light
Class	Endogenous Antioxidant Tripeptide

Research Background

Glutathione is the most abundant intracellular non-protein thiol and the body primary endogenous antioxidant. The GSH/GSSG ratio serves as a key indicator of cellular redox status. GSH functions through direct ROS scavenging, serving as cofactor for glutathione peroxidase, conjugating xenobiotics via GST, and maintaining protein thiol redox state.

The 1500 mg configuration is manufactured under strict quality control with HPLC, MS, and AAA verification. Batch-specific COA included. Bulk and OEM configurations available.

Molecular Mechanisms

Direct ROS Scavenging

Thiol group directly reduces H2O2, superoxide, hydroxyl radical, and peroxynitrite.

GPx Cofactor

Glutathione peroxidase uses GSH as electron donor: 2 GSH + H2O2 to GSSG + 2 H2O. GSSG recycled by glutathione reductase using NADPH.

Xenobiotic Detoxification

GST conjugates GSH to electrophilic xenobiotics for mercapturic acid excretion. Major Phase II detoxification pathway.

Research Applications

Cellular Redox Biology
Oxidative Stress Research
GPx/GST Detoxification Pathways
Protein Thiol Redox Regulation

Comparative Analysis

Compared to NAC: NAC is a GSH precursor requiring biosynthesis. GSH is the active antioxidant. NAC = prodrug; GSH = direct antioxidant cofactor.

Quality Specifications

Parameter	Method	Specification
Purity	HPLC 214nm C18	≥99.0%
Identity	ESI-MS	~307.3 Da
Appearance	Visual	White to off-white powder
Peptide Content	AAA	≥80% net peptide
Moisture	Karl Fischer	≤3%
Endotoxin	LAL	≤0.5 EU/mg

Available Configurations

Configuration	Content	Best For
Standard Kit	1500 mg × 10 vials	Evaluation
Bulk Kit	Custom × 10 vials	Chronic studies
OEM	Custom	Branded products

FAQ

Q: Glutathione vs NAC?

NAC is a precursor converted to GSH through rate-limited biosynthesis. GSH is the active antioxidant. NAC = prodrug approach; GSH = direct cofactor.

Wholesale Pricing

Volume	Discount	For
1 kit	List price	Evaluation; competitive analysis
5+ kits	10% off	Initial portfolio expansion
20+ kits	20% off	Mid-size distributors
50+ kits	30% off	Regional distributors

Resource	Description
Healing Regenerative Peptides Hub	Complete research overview & methodology hub
Glutathione 1500 Mg Research Compound Us	Related research peptide product
Glutathione 600Mg	Related research peptide product
Peptides In Skincare And Weight Loss Research	Latest research insights & methodology

View Complete Research Guide »

Compliance

FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use. Not a dietary supplement or pharmaceutical.

Glutathione 1500 mg