GHRP-6 10 mg
Research PeptideGHRP-6 (Growth Hormone Releasing Peptide-6) 10 mg × 10 vials — Research-Grade Ghrelin Mimetic / GHS-R1a Agonist
Document ID: HKPW-ghrp-6-acetate-10-mg-research-peptide-us-v1.0 | Reviewed by: HKPEPTIDE WORLDWIDE Research Team | Last Updated: 2026-08-08
Product Identity & Specifications
| Parameter | Specification |
|---|---|
| Product Name | GHRP-6 (Growth Hormone Releasing Peptide-6) |
| Dosage | 10 mg × 10 vials |
| CAS Number | 87616-84-0 |
| Molecular Formula | C₄₆H₅₆N₁₂O₆ |
| Molecular Weight | ~873.0 Da |
| Sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ |
| Purity | ≥99% HPLC |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or bacteriostatic water |
| Storage | 2–8°C, desiccated, protected from light |
| Classification | Ghrelin Mimetic / GHS-R1a Agonist |
Research Background
GHRP-6 is the prototypical ghrelin receptor agonist and the most orexigenic GHRP peptide. Its hexapeptide sequence closely mimics the N-terminal active core of ghrelin, producing potent activation of both GH-releasing and appetite-stimulating GHS-R1a signaling pathways. The acetate salt form is supplied for optimal research reconstitution.
The 10 mg × 10 vials configuration is manufactured under strict quality control protocols. Each batch undergoes HPLC purity verification, ESI-MS identity confirmation, and amino acid analysis. A batch-specific Certificate of Analysis (COA) is included with every order. Bulk and OEM configurations available for qualifying wholesale accounts.
Molecular Mechanisms
GHS-R1a Agonism
High-affinity ghrelin receptor binding → dual signaling: (1) pituitary GH release via PLC/Ca²⁺, (2) hypothalamic NPY/AgRP neuron activation → hunger signaling.
NPY/AgRP Activation
GHS-R1a on arcuate nucleus NPY/AgRP neurons → the most potent orexigenic circuit in the mammalian brain. GHRP-6 activates this pathway more strongly than GHRP-2 or Ipamorelin.
GI Motility
Ghrelin-mimetic activity on enteric neurons → gastric emptying and intestinal transit via vagal afferent activation.
Research Applications
- Ghrelin Pathway Research
- Feeding Behavior Studies
- GH Secretion Models
- GI Motility Research
Comparative Analysis
Compared to GHRP-2: GHRP-6 produces stronger hunger signaling (closer to ghrelin). GHRP-2 is more potent for GH but with less appetite. GHRP-6 is the tool of choice for full ghrelin-mimetic (GH + hunger) studies.
Quality Control & Analytical Specifications
| Parameter | Method | Specification |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity (MW) | ESI-MS | ~873.0 Da |
| Appearance | Visual inspection | White to off-white powder |
| Peptide Content | Amino acid analysis | ≥80% net peptide |
| Residual Moisture | Karl Fischer titration | ≤3% |
| Endotoxin | LAL assay | ≤0.5 EU/mg |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 10 mg × 10 vials × 10 vials | Evaluation; protocol validation |
| Bulk Kit | Custom × 10 vials | Chronic studies; repeat orders |
| OEM/Private Label | Custom | Branded product development |
Frequently Asked Questions
Q: Why does GHRP-6 increase hunger?
GHRP-6 closely mimics ghrelin’s N-terminal active core. Its His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ sequence strongly activates NPY/AgRP neurons — the most powerful appetite circuit. This is an intentional feature, not a side effect.
Q: How is GHRP-6 different from GHRP-2?
GHRP-6: stronger hunger, closer ghrelin mimic. GHRP-2: more potent GH release, less appetite. Choice depends on whether the research model requires full ghrelin-profile activation.
Q: What documentation is provided?
≥99% HPLC, ESI-MS, chiral HPLC (D-Trp², D-Phe⁵ verification), amino acid analysis. Batch-specific COA.
Tiered Wholesale Pricing
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
Contact our team for 100+ kit custom pricing. Mixed-molecule orders qualify for combined volume tiers.
Related Research & Resources
| Resource | Description |
|---|---|
| Healing Regenerative Peptides Hub | Complete research overview & methodology hub |
| Ghrp 6 Acetate 10 Mg Research Peptide Us | Related research peptide product |
| Ghrp 6 Acetate 5 Mg Peptide Research Com | Related research peptide product |
| Why Muscle Growth Peptide Research Is Expanding | Latest research insights & methodology |
View Complete Research Guide »
Compliance Statement
FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary diagnostic, therapeutic, or prophylactic use. Not a dietary supplement, pharmaceutical ingredient, or approved drug. Researchers must comply with all applicable institutional, local, and national regulations.
© 2026 HKPEPTIDE WORLDWIDE. All rights reserved. Document ID: HKPW-ghrp-6-acetate-10-mg-research-peptide-us-v1.0