BPC-157 5 mg
Research PeptideBody Protection Compound-157 5 mg × 10 vials — Research-Grade Cytoprotective Pentadecapeptide
Document ID: HKPW-bpc-157-5-mg-body-protection-research-pe-v1.0 | Reviewed by: HKPEPTIDE WORLDWIDE Research Team | Last Updated: 2026-08-08
Product Identity & Specifications
| Parameter | Specification |
|---|---|
| Product Name | Body Protection Compound-157 |
| Dosage | 5 mg × 10 vials |
| CAS Number | 137525-51-0 |
| Molecular Formula | C₆₂H₉₈N₁₆O₂₂ |
| Molecular Weight | 1419.5 Da |
| Sequence | H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH |
| Purity | ≥99% HPLC |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or bacteriostatic water |
| Storage | 2–8°C, desiccated, protected from light |
| Classification | Cytoprotective Pentadecapeptide |
Research Background
BPC-157 is a partial sequence of Body Protection Compound (BPC), a protein isolated from human gastric juice with potent cytoprotective and tissue repair properties. The 15-amino acid pentadecapeptide fragment retains the complete healing-promoting activity of the full protein, making it one of the most extensively studied regenerative peptides in preclinical research. Its stability in gastric acid enables oral administration in GI research models — a property almost unique among bioactive peptides.
The 5 mg × 10 vials configuration provides an optimal quantity for [specific protocol type] research designs. Each vial is manufactured under strict quality control protocols with full analytical documentation including HPLC purity verification and mass spectrometry identity confirmation.
Molecular Mechanisms
VEGF-Mediated Angiogenesis: Upregulates vascular endothelial growth factor (VEGF) at injury sites → new capillary formation → enhanced tissue perfusion. Documented in tendon, ligament, bone, and skin wound models. PMID references available upon request.
Growth Hormone Receptor Modulation: Upregulates GH receptors specifically on injured tissue → amplifies local GH signaling without affecting systemic GH levels. Tissue-specific receptor sensitization.
Nitric Oxide System: Modulates eNOS activity → NO-mediated vasodilation → improved microvascular blood flow to wound beds. Endothelial-protective effect.
FAK-Paxillin Pathway: Activates focal adhesion kinase → fibroblast and keratinocyte migration into wound beds → accelerated re-epithelialization.
Anti-Inflammatory: Reduces TNF-α and IL-1β; promotes M2 macrophage polarization → resolution of inflammation.
Research Applications
- Tendon & Ligament Healing Research
- Gastric Mucosal Protection
- Wound Healing & Angiogenesis
- Bone Fracture Repair
- CNS Injury & Neuroprotection
Comparative Analysis
Compared to TB-500: BPC-157 primarily drives angiogenesis via VEGF/GH receptor pathways. TB-500 drives cell migration via actin sequestration. Combined (BPC-157/TB-500 blend): synergistic — BPC creates vessels, TB mobilizes cells.
Quality Control & Analytical Specifications
| Parameter | Method | Specification |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99% HPLC |
| Identity (MW) | ESI-MS | 1419.5 Da |
| Appearance | Visual inspection | White to off-white powder |
| Peptide Content | Amino acid analysis | ≥80% net peptide |
| Residual Moisture | Karl Fischer titration | ≤3% |
| Endotoxin | LAL assay | ≤0.5 EU/mg |
| Sterility | Membrane filtration | Sterile-filtered |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 5 mg × 10 vials × 10 vials | Evaluation; protocol validation |
| Bulk Kit | Custom dosage × 10 vials | Chronic studies; repeat orders |
| OEM/Private Label | Custom configurations | Branded product development |
Frequently Asked Questions
Q: Why is BPC-157 stable in gastric acid?
BPC-157 is derived from a gastric juice protein that evolved to function in acidic environments. Its proline-glycine-rich sequence confers remarkable resistance to pepsin and acid hydrolysis — unique among bioactive peptides. This enables oral administration in GI research without enteric coating.
Q: What is the BPC-157 + TB-500 synergy?
BPC-157 drives angiogenesis (new blood vessel formation); TB-500 drives cell migration (actin dynamics). Together: BPC creates the vascular infrastructure, TB mobilizes the cellular repair machinery. The 10mg + 10mg blend kit provides both mechanisms in one batch-documented product.
Q: What purity analysis is provided?
≥99% HPLC at 214nm, ESI-MS identity (±1.0 Da), amino acid analysis (>80% net peptide), Karl Fischer moisture (≤3%). Full COA with every order.
Q: What salt forms are available?
Standard: Acetate salt (TFA cleavage + acetate counterion exchange). Available on request: Arginine salt for enhanced aqueous solubility at neutral pH. Specify salt preference when ordering.
Q: How should BPC-157 be stored?
Lyophilized: 2-8°C, desiccated, 24-month stability. Reconstitute in sterile PBS (pH 7.0-7.4). Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Tiered Wholesale Pricing
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
Contact our team for custom volume pricing on 100+ kit orders.
References & Further Reading
- Scientific literature available upon request for qualified research institutions
- Batch-specific Certificate of Analysis (COA) included with every order
- Full HPLC chromatogram and MS spectrum available on request
- Technical dossier provided with bulk wholesale orders
Related Research & Resources
| Resource | Description |
|---|---|
| Healing Regenerative Peptides Hub | Complete research overview & methodology hub |
| Bpc 157 5 Mg Body Protection Research Pe | Related research peptide product |
| Bpc 157 Tb 500 10 Mg Research Peptide Co | Related research peptide product |
| Why Anti Aging Peptide Research Is Growing Rapidly | Latest research insights & methodology |
View Complete Research Guide »
Compliance Statement
FOR LABORATORY RESEARCH USE ONLY. This product is intended exclusively for in vitro laboratory research and scientific investigation. Not for human or veterinary diagnostic, therapeutic, or prophylactic use. Not a dietary supplement, pharmaceutical ingredient, or approved drug substance. All researchers must comply with applicable institutional, local, and national regulations governing research chemical use.
© 2026 HKPEPTIDE WORLDWIDE. All rights reserved. Document ID: HKPW-bpc-157-5-mg-body-protection-research-pe-v1.0