BPC-157 5 mg

BPC-157 5 mg

Research Peptide

Body Protection Compound-157 5 mg × 10 vials — Research-Grade Cytoprotective Pentadecapeptide

Document ID: HKPW-bpc-157-5-mg-body-protection-research-pe-v1.0 | Reviewed by: HKPEPTIDE WORLDWIDE Research Team | Last Updated: 2026-08-08

Product Identity & Specifications

ParameterSpecification
Product NameBody Protection Compound-157
Dosage5 mg × 10 vials
CAS Number137525-51-0
Molecular FormulaC₆₂H₉₈N₁₆O₂₂
Molecular Weight1419.5 Da
SequenceH-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH
Purity≥99% HPLC
AppearanceWhite to off-white lyophilized powder
SolubilitySoluble in sterile water or bacteriostatic water
Storage2–8°C, desiccated, protected from light
ClassificationCytoprotective Pentadecapeptide

Research Background

BPC-157 is a partial sequence of Body Protection Compound (BPC), a protein isolated from human gastric juice with potent cytoprotective and tissue repair properties. The 15-amino acid pentadecapeptide fragment retains the complete healing-promoting activity of the full protein, making it one of the most extensively studied regenerative peptides in preclinical research. Its stability in gastric acid enables oral administration in GI research models — a property almost unique among bioactive peptides.

The 5 mg × 10 vials configuration provides an optimal quantity for [specific protocol type] research designs. Each vial is manufactured under strict quality control protocols with full analytical documentation including HPLC purity verification and mass spectrometry identity confirmation.

Molecular Mechanisms

VEGF-Mediated Angiogenesis: Upregulates vascular endothelial growth factor (VEGF) at injury sites → new capillary formation → enhanced tissue perfusion. Documented in tendon, ligament, bone, and skin wound models. PMID references available upon request.

Growth Hormone Receptor Modulation: Upregulates GH receptors specifically on injured tissue → amplifies local GH signaling without affecting systemic GH levels. Tissue-specific receptor sensitization.

Nitric Oxide System: Modulates eNOS activity → NO-mediated vasodilation → improved microvascular blood flow to wound beds. Endothelial-protective effect.

FAK-Paxillin Pathway: Activates focal adhesion kinase → fibroblast and keratinocyte migration into wound beds → accelerated re-epithelialization.

Anti-Inflammatory: Reduces TNF-α and IL-1β; promotes M2 macrophage polarization → resolution of inflammation.

Research Applications

  • Tendon & Ligament Healing Research
  • Gastric Mucosal Protection
  • Wound Healing & Angiogenesis
  • Bone Fracture Repair
  • CNS Injury & Neuroprotection

Comparative Analysis

Compared to TB-500: BPC-157 primarily drives angiogenesis via VEGF/GH receptor pathways. TB-500 drives cell migration via actin sequestration. Combined (BPC-157/TB-500 blend): synergistic — BPC creates vessels, TB mobilizes cells.

Quality Control & Analytical Specifications

ParameterMethodSpecification
PurityHPLC at 214 nm, C18 column≥99% HPLC
Identity (MW)ESI-MS1419.5 Da
AppearanceVisual inspectionWhite to off-white powder
Peptide ContentAmino acid analysis≥80% net peptide
Residual MoistureKarl Fischer titration≤3%
EndotoxinLAL assay≤0.5 EU/mg
SterilityMembrane filtrationSterile-filtered

Available Configurations

ConfigurationContentBest For
Standard Kit5 mg × 10 vials × 10 vialsEvaluation; protocol validation
Bulk KitCustom dosage × 10 vialsChronic studies; repeat orders
OEM/Private LabelCustom configurationsBranded product development

Frequently Asked Questions

Q: Why is BPC-157 stable in gastric acid?

BPC-157 is derived from a gastric juice protein that evolved to function in acidic environments. Its proline-glycine-rich sequence confers remarkable resistance to pepsin and acid hydrolysis — unique among bioactive peptides. This enables oral administration in GI research without enteric coating.

Q: What is the BPC-157 + TB-500 synergy?

BPC-157 drives angiogenesis (new blood vessel formation); TB-500 drives cell migration (actin dynamics). Together: BPC creates the vascular infrastructure, TB mobilizes the cellular repair machinery. The 10mg + 10mg blend kit provides both mechanisms in one batch-documented product.

Q: What purity analysis is provided?

≥99% HPLC at 214nm, ESI-MS identity (±1.0 Da), amino acid analysis (>80% net peptide), Karl Fischer moisture (≤3%). Full COA with every order.

Q: What salt forms are available?

Standard: Acetate salt (TFA cleavage + acetate counterion exchange). Available on request: Arginine salt for enhanced aqueous solubility at neutral pH. Specify salt preference when ordering.

Q: How should BPC-157 be stored?

Lyophilized: 2-8°C, desiccated, 24-month stability. Reconstitute in sterile PBS (pH 7.0-7.4). Aliquot and store at -20°C. Avoid freeze-thaw cycles.

Tiered Wholesale Pricing

VolumeDiscountFor
1 kitList priceEvaluation; competitive analysis
5+ kits10% offInitial portfolio expansion
20+ kits20% offMid-size distributors
50+ kits30% offRegional distributors

Contact our team for custom volume pricing on 100+ kit orders.

References & Further Reading

  • Scientific literature available upon request for qualified research institutions
  • Batch-specific Certificate of Analysis (COA) included with every order
  • Full HPLC chromatogram and MS spectrum available on request
  • Technical dossier provided with bulk wholesale orders
ResourceDescription
Healing Regenerative Peptides HubComplete research overview & methodology hub
Bpc 157 5 Mg Body Protection Research PeRelated research peptide product
Bpc 157 Tb 500 10 Mg Research Peptide CoRelated research peptide product
Why Anti Aging Peptide Research Is Growing RapidlyLatest research insights & methodology

View Complete Research Guide »

Compliance Statement

FOR LABORATORY RESEARCH USE ONLY. This product is intended exclusively for in vitro laboratory research and scientific investigation. Not for human or veterinary diagnostic, therapeutic, or prophylactic use. Not a dietary supplement, pharmaceutical ingredient, or approved drug substance. All researchers must comply with applicable institutional, local, and national regulations governing research chemical use.


© 2026 HKPEPTIDE WORLDWIDE. All rights reserved. Document ID: HKPW-bpc-157-5-mg-body-protection-research-pe-v1.0